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The medium was changed every day for 6 days

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Skin reactions and abscesses at the injection site Even pure peptides can cause local reactions including redness, swelling, bruising, and abscess formation

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Key design elements: Population: 145 adults (18 years) with NF1 and at least one symptomatic, inoperable PN measurable by volumetric MRI, randomized 1:1 to selumetinib (n=71) or placebo (n=74) for 12 cycles Inoperability criteria: PN defined as inoperable due to encasement of or proximity to vital structures, invasiveness, or high vascularity Primary endpoint: Confirmed ORR by cycle 16, assessed by independent central review using Response Evaluation in Neurofibromatosis and Schwannomatosis (REiNS) criteria, where response is defined as 20% reduction in PN tumor volume Results from KOMETs primary analysis, presented at ASCO 2025 and published in The Lancet , demonstrated: ORR 20% (14/71, 95% CI: 11.230.9) in the selumetinib arm vs

A lightweight gel formula delivers hydration without clogging pores or leaving behind a heavy or greasy residue