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A triple-threat in detoxification: the glutathione S-transferases

doi: 10.3389/fimmu.2025.1702860 Received 10 September 2025 Accepted 20 October 2025 Published 30 October 2025 Volume 16 - 2025 Edited by Jorge B

Not all of these steps from oxidative attack to final hemolysis have been fully documented in vivo, in part because of one major difficulty: in the course of AHA the red blood cells sampled from the patient are obviously, at any given stage, those that have not yet hemolyzed

In addition to enzymatic properties, structural investigations on catalytic domains of the enzymes have been also performed

The latest Human UniProtKB/SwissProt Release (2018_10 has 551,681 entries) was used for searching MS/MS spectra
