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Studies assessing the capacity of human brain mitochondrial respiration have shown that mitochondria derived from males create two-fold more reactive oxygen species (ROS) than those of females [38]

Zhang Z, Zuo L, Song X, Wang L, Zhang Y, Cheng Y, et al
The chronobiology of human heart failure: clinical implications and therapeutic opportunities

These signals converge to activate the NLRP3 inflammasome, a multiprotein complex that drives the maturation of IL-1 and IL-18, sustaining chronic inflammation [16]

& Salvemini, D

Development and preliminary evaluation of a training method to assist professionals in reporting suspected child maltreatment
