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As we age, our body has diminished ability to fight free radicals

Glutathione Metabolism and Parkinsons Disease Free Radic Biol Med

[DOI] [PMC free article] [PubMed] [Google Scholar] 53.Dadheech G., Mishra S., Gautam S., Sharma P

This reduction may result in part from the fact that turnover of cysteine S -conjugates derived from halogenated alkenes can result in syncatalytic inactivation of cysteine S -conjugate -lyases (Catalytic Mechanism of the Cysteine S-Conjugate -Lyase Reaction and Syncatalytic Inactivation section)

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Five distinct GPx isozymes have been characterized in mammals, (Table 1) [12]