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Alterations in anxiety-like behavior following knockout of the uncoupling protein 2 (ucp2) gene in mice

SARS-CoV-2 infection of astrocytes via NRP1 hijack could disrupt normal neuron function, induce neuronal cell death leading to abnormal manifestations in the CNS 312

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A dedicated phase 3 RENEW trial which investigates the efficacy and safety of the drug in patients with obesity or who were overweight, but without associated comorbidities is scheduled to start in late 2025.

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