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Studies show that it more readily crosses the cell membrane than glutathione itself

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Moreover, they showed that sesamol prevented gut barrier damage by enhancing the expression of tight junction proteins (occludin, claudin-1, and ZO-1), recovering the loss of gut mucus layer while increasing SCFAs through changes in the gut microbiome structure by enhancing the relative abundance of Coprococcuscus, Butyricicoccus, Odoribacter, and AF12 [470]

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[DOI] [Google Scholar] 37.Verhoeven D.T., Verhagen H., Goldbohm R.A., van den Brandt P.A., van Poppel G