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The relevance of lipid markers (SM, PC, cholesterol) to neuroinflammation-mediated reinjury of TBI brains is supported by the timeline of their release into the CSF both acutely and again at 4 days postinjury in patients [45]

PLoS One 13, e0193568.Google Scholar Dangour, AD, Allen, E, Elbourne, D et al

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Once activated, these macrophages promote the release of pro-inflammatory factors like tumor necrosis factor- (TNF-), activate signaling pathways including NF-B, and drive neuroinflammation throughout the body and brain [40]

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