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Bridging necrosis may ultimately give rise to bridging fibrosis

**Patch Test:** Before applying to your entire face, perform a patch test on a small, inconspicuous area of your skin (e.g., behind the ear or on the inner forearm), and wait 24 hours to check for any adverse reactions

This contact time allows sublingual absorption to occur

doi:10.1083/jcb.200511093

Since AML models with KMT2A rearrangements are particularly sensitive to PL treatment, we performed colony-forming cell (CFC) assays to determine whether PL affects the ability of AML cell lines harbouring KMT2A rearrangements (MV-4-11, MOLM-13, Cas9 Flt3-ITD MLL-AF4 and MLL-AF9) to initiate colony formation, an in vitro surrogate for leukaemia stem/progenitor activity

And it was bothering me so much