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When evaluating the differences in the construction of the NALFD/NASH model between the two methods, it was found that the MCD diet could spontaneously lead to liver fibrosis within 24 weeks and significantly affect the expression of genes involved in liver fibrosis pathways

doi: 10.1111/jhn.12372

[Google Scholar] Anderson L.E., Ringenberg M.R., Carol A.A

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Multifactorial therapeutic and preventive management strategies could be established and more specifically adjusted to patients, depending on their gut bacteria composition

Here, we describe an Fc-engineering approach, based on three amino acid substitutions (Q311R/M428E/N434W) (REW), which improves pH-dependent human FcRn binding