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Sample type Dilution factor Human serum 1 Mouse serum 3-5 Rat serum 5-8 10% Mouse brain tissue homogenate 1 10% Rat liver tissue homogenate 30-60 HepG2 cell homogenate (5 mgprot/mL) 1 10% Plant tissue homogenate 1-5

Frias, S

doi: 10.3390/toxins2040771

Function and regulation of GPX4 in the development and progression of fibrotic disease

While DAMGO triggers MOR internalization by recruiting either arrestin 2 or 3, morphine selectively interacts with arrestin 3 which is recruited at the plasma membrane to promote MOR internalization (Groer et al., 2011)

However, acetaminophen toxicity has been implicated in a wide range of other disorders in humans and/or experimental animals including cancer, birth defects, asthma, allergies, and brain toxicity (Table 1)