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More comprehensive studies are needed to investigate the long-term effects of these diets and interventions and to what extent they are useful in clinical practice
The iodine content of commercially available seaweeds may vary greatly, making it difficult to estimate an accurate average value, and some seaweed may largely exceed the TUL, exposing to iodine excess [32]
Antioxid Redox Signal 2004
10.1128/mcb.24.7.2593-2604.2004 27 HoushmandF.FaghihiM.ZahediaslS
In BV2 microglial cells, BV2-metformin-loaded PLGA treatment downregulated inducible nitric oxide synthase (iNOS) expression (proinflammatory M1 phenotype) and upregulated mannose receptor (CD206) expression (anti-inflammatory M2 phenotype), leading to a more than three-fold elevation in the CD206/iNOS fluorescence intensity ratio
environmental factors like diet and exercise can narrow the gap
