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In response to environmental stresses such as increased temperature, the conserved transcription factor HSF-1 binds to heat shock elements (HSEs) 1 in the promoters of heat-inducible genes and induces expression of heat shock proteins (HSPs) and molecular chaperones
Vitamin C also participates in redox recycling of other important antioxidants
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In addition, a combination of pre- and post-treatments with TRF conferred better protection against oxidative DNA damage than either pre- or post-treatment with TRF alone
