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For these reasons, the true global prevalence is almost certainly higher than current official estimates
Cell free Hb, its oxidation products and heme that is released from oxidized Hb forms are potential DAMPs

doi: 10.1016/S1474-4422(18)30490-3 14 AtenS.KiyoshiC

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The authors reported that these effects were associated with reduced apoptosis during the in vitro aging window and suggested that Epitalon may delay oocyte aging through modulation of mitochondrial activity and oxidative stress
