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In 2009, the FDA issued a black box warning for Botox and other BTX injections after a number of cases occurred where the drug spread far beyond the injection site

doi: 10.3389/fmicb.2020.00299

Metabolic abnormalities such as insulin resistance and lipid overload adversely affect cardiac function

Ozempic is a glucagon-like peptide-1 (GLP-1) receptor agonist, which is used as a once-weekly subcutaneous injection to improve blood glucose control in adults with type 2 diabetes and reduce the risk of major cardiovascular events in patients with established cardiovascular disease, and lower the risk of kidney failure in patients with chronic kidney disease and type 2 diabetes

Animal studies and case reports were excluded

If you have any concerns or questions, consult a medical expert or your supervisor for guidance