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10.3390/ijms22116107 60 JenkinsR

doi: 10.1016/s0009-9236(98)90147-3

Lin R, Wu W, Chen H, Gao H, Wu X, Li G, et al

Reductive Stress Induced by NAD(P)H and GSH As discussed in the Cellular Redox Network and Redox Stress section, NAD(H) can modulate energy metabolism

Key points Historical note and terminology Key points Pyruvate dehydrogenase complex deficiency was first described in 1970 in a 9-year-old boy with an intermittent combined cerebellar and choreoathetoid movement disorder determined to be due to an inherited defect in pyruvate decarboxylase (aka, the initial step in the catalytic oxidative decarboxylation of pyruvate to acetyl-CoA by pyruvate dehydrogenase complex) (10)

Research-use disclaimer: The peptides and methods discussed are intended strictly for laboratory and in-vitro research use, not for human or animal consumption
