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32 At this stage, some patients may experience pathological changes, such as intestinal stricture and perforation, as well as serious complications, including severe abdominal pain, severe diarrhea, and high fever

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Many studies in human and animal models suggested that the deposition of the drugs sprayed by some nasal devices was higher in the olfactory region than the deposition of the drugs sprayed by traditional Nasal sprays

References Campbell, R., Bellolio, F., Motosue, M., et al

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