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doi: 10.1016/j.bcp.2009.02.024

For example, exosomes secreted by metastatic melanoma cells can instigate a pro-inflammatory gene signature in both lung fibroblasts and brain astrocytes, which promotes the formation of an inflammatory metastatic niche, suggesting that the reprogramming of stromal cells by tumor cell exosomes is a general mechanism in distant organs

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The kynurenine pathway: a finger in every pie

In conclusion, BPC 157 promotes the ex vivo outgrowth of tendon fibroblasts from tendon explants, cell survival under stress, and the in vitro migration of tendon fibroblasts, which is likely mediated by the activation of the FAK-paxillin pathway

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