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[ 14 ] BACH1 can also recruit a histone H3K4me1/2 demethylase named lysinespecific demethylase 2 (LSD2), bind to p53 R175H and form BACH1p53 R175H LSD2 complex, which modifies histone methylation status at the promoter of BACH1 targets and subsequently activates the genes transcription

10.1111/j.1365-313x.2005.02441.x Plant J

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This patient's explicit statement that he is not ready to quit indicates that highlighting his COPD chronicity will likely increase resistance rather than foster motivation

Quantitative real-time PCR Total RNA was extracted from homogenized tissue or cell culture and reverse transcribed as described previously (Schleicher et al, 2016)