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(2) Reduced microbiota -diversity generates individualized metabolic phenotypes, with specific bacterial consortia (e.g., Bacteroidetes/Firmicutes ratios) exhibiting strong correlations with insulin sensitivity

Supplementation mediated improvement of Gpx1 gene expression may reflect a possible increase of the cellular antioxidant defence capacity, as Gpx1 encodes a key glutathione peroxidase enzyme, which is involved in the detoxification of ROS, including hydrogen peroxide and lipid hydroperoxides, thereby potentially contributing to attenuation of oxidative stress (Quintana-Cabrera et al., 2012

Effects of endurance training on mitochondrial ultrastructure and fiber type distribution in skeletal muscle of patients with stable chronic heart failure