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Pathologically, -Syn is subjected to a conformational change from -helical state to -sheet-rich oligomers and fibrils capable of aggregation due to mutations in its encoding gene SNCA, altering SNCA gene transcription and mRNA stability or processing (Nalls et al., 2019

Modulation of multidrug resistance p-glycoprotein activity by flavonoids and honokiol in human doxorubicin-resistant sarcoma cells (MES-SA/DX-5): implications for natural sedatives as chemosensitizing agents in cancer therapy

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Metabolites in the transmethylation and transsulfuration pathways, responsible for glutathione production are imbalanced in those with this disorder

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