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GRd, glutathione reductase

GSH plays a vital role in cellular redox homeostasis in the nervous system and protects neurons against a variety of oxidative insults

Due to their genetic similarity to humans and transparency during early vertebrate development, they are well-established models for biocompatibility studies 63

Proc Natl Acad Sci USA 98 : 1159811603 Olchovsky D, Song J, Gelato MC, Sherwood J, Spatola E, Bruno JF, Berelowitz M (1993) Pituitary and hypothalamic insulin-like growth factor-I (IGF-I) and IGF-I receptor expression in food-deprived rats

Novel strategies have been established based on advances in nanotechnology to cross the BBB (7)

PLoS One 11 (8), e0160620