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This support previous works that showed a disruption of Wnt proteins by neonatal exposure to GBH (2 mg/kg bw/day) from PND1 to PND7, in rat uterus (PND21) and implantation sites (GD9) ( Table 1 )

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First, these therapeutics face limitations such as poor targeting to the site of atherosclerotic plaques and the need for prolonged use, which can lead to undesirable side effects like kidney damage and bleeding
Kalantar-Zadeh, K., Rodriguez, R

The discovery of active receptors in porcine testis and in bovine spermatozoa cells has ratified the action of GH and IGF-1 on sperm cells [88]
