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Finally, in phase III, the conjugated xenobiotics may be further processed, before being recognised by efflux transporters and pumped out of cells

10.1371/JOURNAL.PONE.0039006 [DOI] [PMC free article] [PubMed] [Google Scholar] Wu LH, Huang BR, Lai SW et al (2020) SIRT1 activation by minocycline on regulation of microglial polarization homeostasis

All analyses were performed using R software version 4.2.3, utilizing the dplyr, data.table, and ggplot2 packages

Glutamate Modulation: NMDA receptor antagonists (e.g., memantine) and AMPA receptor antagonists are also used to prevent glutamate-mediated excitotoxicity and reduce seizure frequency