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To determine if the changes in astrocyte morphology impacted bloodbrain barrier coverage, socially defeated mice were injected 24 h after their last stress session with a fluorescently tagged dextran that is unable to cross the bloodbrain barrier under normal conditions and examined if this signal was present in the ME/ARC of these mice in comparison with similarly injected nonstressed mice

Vitamin E naturally occurs in eight different chemical forms, including alpha-tocopherol and gamma-tocopherol (Albanes 1996

The Nrf-2/HO-1 Signaling Axis: A Ray of Hope in Cardiovascular Diseases

Certara, Sheffield, UK)

Following treatment with GHK or GHK-PEG, the number of cells per ml of media was assessed as previously described and the rate of cell proliferation was expressed as fold control and compared between treated and non-treated cells using analysis of variance (ANOVA)