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Nicotinamide restriction with subsequent depletion of cellular NAD was shown to increase oxidative stress-induced DNA damage in a precancerous skin cell model, implying a protective role of NAD-dependent pathways in cancer (63)

Boosting antioxidant defense while suppressing inflammatory signals explains why one peptide protects multiple organ systems from a single alcohol exposure

JAmChemSoc 54:12121221 McEwen W (1936) A further study of extremely weak acids
