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While the flow cytometric apoptosis reduction (3.48%) was not statistically significant, the molecular markers (caspase-3 down 42.7%, PARP down 77.5%, Bcl-2/Bax shift) were all highly significant

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FOXO4-DRI competitively disrupts this interaction, potentially restoring apoptotic signaling specifically in senescent cell populations

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The reaction is more pronounced under certain specific conditions

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Future Recommendations from the Absorbuddy Team Future experiments should address the unanswered questions on the structural and functional determinants of cross-species IFB12 binding

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Environmental Science & Technology, 57 (12), 47634774

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