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Evidence for the aldo-keto reductase pathway of polycyclic aromatic trans-dihydrodiol activation in human lung A549 cells

Further studies confirmed Gboxin accumulation and growth inhibition in GBM allografts and patient derived xenografts, providing additional validation of OXPHOS as a viable therapeutic target in GBM

Ethics declarations Competing interests SJW is the founder of Ridgeline Therapeutics, HN is a paid employee of Ridgeline Therapeutics and, since manuscript submission, ADW has also become a paid employee of Ridgeline Therapeutics

This measurement at 10 weeks indicates that the DR disease model was successfully established

Metformin antagonizes cancer cell proliferation by suppressing mitochondrial-dependent biosynthesis