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doi: 10.1210/endrev/bnaa027 51

Lancet 365:6378 [DOI] [PubMed] [Google Scholar] Antolin I, Mayo JC, Sainz RM, de los Angeles del Brio L, Herrera F, Martin V, Rodriguez C (2002) Protective effect of melatonin in a chronic experimental model of Parkinsons disease

This multi-core design maintained the viability of both probiotics (each core provided a protected micro-environment) and leveraged their synergistic interactions- the microcapsules exhibited enhanced acid resistance and in vivo efficacy, significantly reducing intestinal inflammation and improving metabolic markers in an animal model

Common side effects include abdominal pain (30%), nausea (18-27%), headache (16%), catheter

Nathan CF, Hibbs JB

Your provider will help you pick the timing that works with anything else youre using