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Description
The total protein content of homogenates was determined as above and adjusted to 1 mg/mL with phosphate buffered saline (PBS) with calcium and magnesium (Dubelccos PBS, Invitrogen), supplemented with DNase (Benzonase 100 UI/mL, Merck)

Abbreviations 4E-BP1: Eukaryotic translation initiation factor 4E-binding protein-1 6W: Six-minute walk test AEs: Adverse events BMI: Body mass index Comp: Composite endpoint DXA: Dual-energy X-ray absorptiometry ITT: Intent-to-treat LS: Lower strength MM: Muscle mass mTOR: Mammalian target of rapamycin MuRF1: Muscle RING-finger protein-1 NNHPD: Natural and non-prescription health products directorate NSAID: Non-steroidal anti-inflammatory drug PP: Per-protocol QoL: Quality of life S6K: p70-S6 kinase UPS: Ubiquitinproteasome system US: Upper strength References Fielding RA, Vellas B, Evans WJ, Bhasin S, Morley JE, Newman AB, Abellan Van KG, Andrieu S, Bauer J, Breuille D, Cederholm T, Chandler J, De MC, Donini L, Harris T, Kannt A, Keime GF, Onder G, Papanicolaou D, Rolland Y, Rooks D, Sieber C, Souhami E, Verlaan S, Zamboni M

Randomized controlled trial of oral glutathione supplementation on body stores of glutathione European Journal of Nutrition 5 May 2014): Decreased oxidative stress (After 6 months (250 mg/1,000 mg/day))

12,13-DiHOME: An Exercise-Induced Lipokine That Increases Skeletal Muscle Fatty Acid Uptake
A post hoc analysis of a phase III trial found that administering the drug twice a week was linked to a significantly higher rate of severe BIPN compared to once-weekly dosing (28% vs

Part I: creatine kinase BB, glutamine synthase, and ubiquitin carboxy-terminal hydrolase L-1
