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The oxidation of fatty acids is another pathway for F-A degradation in some species of vertebrates and mammals that occurs in the endoplasmic reticulum of the liver and kidney, it is the oxidation of the carbonthe carbon farthest from the carboxyl group (in contrast to oxidation which occurs at the carboxyl end of fatty acid, in the mitochondria)

[DOI] [PMC free article] [PubMed] [Google Scholar] Brass EP

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Thus, the glycolysis pathway would be downregulated and gluconeogenesis would be upregulated