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However, peripheral antagonist injections do not have consistent effects, due in part to biphasic effects at different doses (Woolverton, 1986

Regularly evaluate patients, particularly when initiating and titrating Hydrocodone Bitartrate and Acetaminophen Tablets and when Hydrocodone Bitartrate and Acetaminophen Tablets are given concomitantly with other drugs that depress respiration [see WARNINGS

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Excitingly, imaging mass spectrometry, in which a tissue slice is coated with matrix and then ionized by a laser pulse (MALDI), offers the prospect of visualizing them at single-cell resolution 180,181 , although proof of principle for PPP metabolites remains to be established