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Critical role for tetrahydrobiopterin recycling by dihydrofolate reductase in regulation of endothelial nitric-oxide synthase coupling: relative importance of the de novo biopterin synthesis versus salvage pathways

The net result of these effects is that there is a decrease in the effective surface area available to the dissolution medium and therefore a fall in the dissolution rate

Yang C, Ma X, Wang Z, Zeng X, Hu Z, Ye Z, et al

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During wound healing, MMPs play dual roles: they facilitate tissue debridement and cell migration in early healing phases, while excessive or prolonged MMP activity can impair matrix deposition and delay closure

doi: 10.1038/s41580-020-00324-8 [DOI] [PMC free article] [PubMed] [Google Scholar] Kabil O, Banerjee R