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Int J Stroke
Oct 27 2021;22(21)doi:10.3390/ijms222111629
Aliment Pharmacol Ther 16(3):361372
First, CIPN is associated with hyperactivity and hyperexcitability in several brain regions including the PAG, thalamus, ACC, S2, and insula, which makes sense as they are part of well-known circuitry related to sensation and perception including pain (Reddan and Wager, 2018)
Gibault, J
141,391 Like TGF-, GDF15 can activate the Smad signaling pathway, the PI3K/Akt signaling pathway, and the NF-B signaling pathway
