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Clinical enthusiasm should remain tempered until larger, independently conducted trials establish both safety and efficacy

Never adjust units based on comparisons to another patient or product

92 , 677687 (2011) Schatz, A., Bugie, E

The transplanted human mesenchymal stem cells survived for at least six months and demonstrated expression of chondrocyte markers and mRNA expression of collagen IIA, IIB, versican, aggrecan, and Sox9 indicating differentiation into disc-like cells