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Studies have shown that the pathogenesis of ARHL is genetically related in 2575% of cases (Viljanen et al., 2007
Therefore, the development of novel and versatile methodologies for modifying AONs with precise control over these critical features remains a significant endeavour 23

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Tesamorelin is utilized in experimental models to investigate growth hormonemodulated effects on adipocyte differentiation, lipid metabolism signaling pathways, and IGF-associated regulatory networks
Primers 5 , 56 (2019)

Small errors in preparation, storage, or administration can undermine an otherwise well-designed protocol
