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Site-directed mutagenesis of human glutathione transferase P1-1

Glutathione plays an important role in the detoxification of reactive oxygen species (ROS) in the central nervous system, where it directly quenches radicals in nonenzymatic reactions and reduces peroxides generated by glutathione peroxidase

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Regulation of de novo purine biosynthesis in human lymphoblasts

The projected system also gets benefited from the partial contribution to the antimicrobial activity from the stable PDA-semiquinone and ROS generated by the metalPDA NPs under physiological conditions as suggested by Yeroslavsky et al