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These results suggest the potential crucial role of DMF, as an apremilast, in the treatment of patients with psoriasis with concurrent metabolic comorbidities, which are probably the largest part

In preclinical models of PDAC, while ablation of the tumour-restrictive -SMA + CAFs reduced survival, depletion of FAP + CAFs significantly improved survival and enhanced the efficacy of immune checkpoint inhibitors (ICIs) [243]

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At least three independent replicates were performed for all experiments with different RNA samples