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In addition, Cu + in the cytoplasm can be transported to the mitochondrial intermembrane space, in which Cu + binds to chaperone cytochrome oxidase 17 (COX17) and is delivered to either the chaperone synthesis of cytochrome oxidase 1 (SCO1) or COX11, ultimately delivering to the cytochrome C oxidase (CCO) I (COX1) or II (COX2) subunits to involve them in the respiratory chain (Horng et al., 2004)

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[DOI] [PubMed] [Google Scholar] 86.Borenshtein D, Schlieper KA, Rickman BH, Chapman JM, Schweinfest CW, Fox JG, et al

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