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doi: 10.3390/antiox6030062

75 LiM.QiM.ZhangH.WangZ.ZhangN.LiQ.et al (2011a)
The disulfide bonds can be reduced at basic conditions using DTT

Isoenzyme-specific quantitative immunoassays for cytosolic glutathione transferases and measurement of the enzymes in blood plasma from cancer patients and in tumor cell lines
New York: Thieme Publishers

For perspective, that level of efficacy means someone weighing 220 pounds could expect to lose approximately 53 pounds over 48 weeks