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Biomarkers for pregnancy complications, possible screening algorithms, and drugs proposed as treatment to these pathologies will be detailed in the subsequent sections

AAV2, adeno-associated viral type-2

doi: 10.1111/hel.12635
The unique pharmacological profile of tirzepatide allows a greater engagement of the GIP receptor, mimicking the actions of native GIP, compared to the GLP-1 receptor, where it activates biased downstream signals favoring cAMP generation over beta-arrestin recruitment, resulting in reduced receptor internalization and degradation 2

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doi: 10.1523/JNEUROSCI.4104-07.2007, 50 la De RosaA.Olaso-GonzalezG.Arc-ChagnaudC.MillanF.Salvador-PascualA.Garca-LucergaC.et al