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Humans express six large families of methyltransferases identified as the homocysteine methyltransferase family, the lysine methyltransferase family, the radical S -adenosylmethionine domain containing family, the seven-beta-strand methyltransferase motif containing family, the SET domain containing family, and the SPOUT methyltransferase domain containing family

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This process creates water or alcohols along with GSSG