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At the methodological level, isotope tracing technologies can directly resolve actual metabolic flux changes, single-cell and spatial multi-omics can help identify cell-cell interactions and substrate competition in the tissue microenvironment, and genome-scale metabolic modeling can be used for priority ranking and assessment of targetability

Diagnosis involves a detailed medical history, sometimes followed by urine or blood antibody testing to confirm the overgrowth

Copper peptides are finally getting the recognition they deserve

For example, ferroptosis, an iron-dependent form of cell death, is characterized by excessive lipid peroxidation on cell membranes

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10.1038/s41467-024-45821-y Nat