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Bentz, S

While the precise mechanism underlying CD38 upregulation in these pathological conditions and disease models are not fully understood, CD38-mediated NAD + consumption leading to NAD + decline and consequent loss of cellular sirtuin activity appears to be a universal mechanism underlying their pathogenesis 24,31

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2011;66(5):33745 Lassus J, Harjola VP

PMC 4545890

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