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As noted earlier, the citrate synthase reaction that condenses oxaloacetate with acetyl-CoA has a standard free energy of about 8 kcal/mol and is responsible for pulling the MDH reaction in the forward direction
In a more recent, rats were fed beetroot juice (8 mLkgbmday 1 for 28 days) and treated with the carcinogen 7,12-dimethylbenz[a]anthracene (DMBA) on day 27 and 28 of the beetroot juice-feeding period study [58]
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