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TRIP12 promotes small-molecule-induced degradation through K29/K48-branched ubiquitin chains

Material was then dissolved in DMEM, and diluted to a final volume of 25 ml with DMEM

Vitamin C is essential for collagen cross-linking

where F is the frequency of an isotopologues, n is the number of potentially labeled atoms in the molecule, x is the number of actually labeled atoms in the molecule, and p is the probability of there being label in the atom (which corresponds either to the tracer enrichment or natural abundance enrichment)

Consequently, the ability of SHFKO to modulate the cross-talk between these two pathways underlies its enhanced therapeutic effects in ameliorating inflammation and promoting lesion repair