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Manna, P., Achari, A

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doi: 10.3389/fonc.2024.1393078 143 HuGGuoMXuJWuFFanJHuangQiet al

Cotransfection of the pMSCVLuciferase reporter vector containing the Gclc 3 UTR (WT or mutant) (1 g/well), a RenillaLuciferase (RenillaLuc) reporter construct (100 ng/well), and either mir18a mimic (50 nM) or control mimic (50 nM) was carried out

The metabolism-enhancing phenotypes of CYP2C19 are responsible for the rapid metabolism of some PPIs and thus influence the reduction in intragastric acidity