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Due to the regular changes of VEGF after tendon injury, some studies have proposed that VEGF and neovascularization are considered as observational indexes and predictors of clinical efficacy in patients with tendon injury before and after treatment (Scott et al., 2008), the duration of symptoms ranged from 5 to 18 months in VEGF-positive patients, and from 6 to 81 months in VEGF-negative patients suffering from patellar tendinopathy, indicating that patients with VEGF expression healed faster than those without VEGF expression (Scott et al., 2008)

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