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Chemical inhibition of the mitochondrial division dynamin reveals its role in Bax/Bak-dependent mitochondrial outer membrane permeabilization

When we tested the effect of the combination of the two inhibitors, CA074 and DFO, on cell line #1, the most resistant to TMZ, we found that while CA074 or DFO alone reduced QN/TMZ-induced cell death of about 30%, their combination was able to reduce cell death of about 50% (Fig

At the molecular level, silybin binds with submillimolar affinity to A oligomers, using its A ring as the primary binding site

Hypertension induced by chemotherapeutic and immunosuppresive agents: a new challenge

Patients on insulin or other glucose-lowering medications need closer monitoring because MOTS-c improves insulin sensitivity, which can amplify the effect of those medications

The social defeat hypothesis of schizophrenia is more topical than ever
