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these data suggested that N-terminal, N-acyl tyrosine containing tripeptides should be biologically active

doi: 10.1128/mBio.01548-14

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Kobayashi, Y., Fukami, T., Shimizu, M., Nakajima, M
Significantly, BPA can activate these pathways at concentrations far below (pM - nM range) 60 those required for nuclear ER binding 63 and activation 64
