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In effect, in order to exert its anti-mitochondrial dysfunction properties facilitating the synthesis of proteins, orotic acid has to be saltified with an organic cation eg, carnitine, for its total solubilization and subsequent ease of absorption

Here, we treated a D2.B10-Dmdmdx/J (D2-mdx) model of DMD (910 wk old) with mitochondrial division inhibitor 1 (Mdivi-1), a selective Drp1 inhibitor, every other day (intraperitoneal injection) for 5 wk

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